I think that depends on how you define ‘civilisation’. My inclination is that most people would say civilisation has ended if life is drastically different to how they perceive their life/world they live in. Think ‘civilisation as we know it’ rather than a dictionary definition.
However, I disagree that it’s not an existentisl threat, if only on the basis of possible crop failiures on a massive scale (reduced crop yields are a global issue already). Don’t underestimate the impact of food shortages on everything else, we in the west have become accustomed to easy access to food.
I think the point is, not that we are completely different people, one moment to the next, but that we should embrace change rather than fight it. Life and the world around us is constantly changing and we are better off for changing with it.
Re your hypothetical letter, you can only address it to the persona you last knew, so to speak. Upon renewed communication, you’ll learn how that person has changed, and maybe you will too a little or a lot.